Research Scientist – CAR-T Therapy Process Development

Job Description

Everyone at Kite is grounded by one common goal – curing cancer. Every single day, we seek to establish an inclusive line between that purpose and our day-to-day work.

The preclinical process development team is seeking a highly motivated Research Scientist to join the group. The Research Scientist will play a key role in the development of CAR T cell manufacturing process focusing on CAR T cell product fitness and metabolism. The role will lead from bench and collaborate with cross-functional teams to support multiple cell therapy programs and advance pipeline candidates.

Responsibilities

• CAR T cell therapy process development and optimization
• T cell characterization focusing on CAR T cell product fitness and metabolism
• Explore T cell metabolic modulation during T cell manufacturing to improve T cell fitness
• Work in close collaboration with cross-functional teams supporting pipeline projects
• Mentor junior scientist in informal setting
• Communicate plans and scientific results in both oral and written forms
• Coordination of tasks across multiple projects, demonstrating prioritization and planning, managing timelines and deliverables
• Keep electronic notebook and batch record.

Basic Qualifications

• Doctorate OR
• Master’s and 6+ years of scientific experience OR
• Bachelor’s and 8+ years of scientific experience

Preferred Qualifications

• Ph.D. in Chemical Engineering/Biomedical Engineering/Immunology/Cancer Biology
• Research experience with a successful publication track record
• Experience with development of unit operations applicable in the manufacturing of genetically engineered T cell based therapy
• Advanced cell culture techniques with preference for human T cell or other immune cell types
• Proficient in utilizing analytical methods characterizing and understanding cell therapy product
• Critical thinking, problem solving, and trouble shooting skills
• Proven track record to be self-motivated, creative, and work both independently and within a highly dynamic team
• Comfortable in a fast-paced company and able to adjust workload based upon changing priorities
• Strong organizational skills and record keeping
• Excellent interpersonal, verbal and written communication skills in a collaborative work environment
• In-depth understanding of immune metabolism
• Knowledge of state-of-art cell therapy bioprocess technologies
• Proficiency in operating closed systems in cell therapy manufacturing

Does this sound like you? If so, apply today!

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