Sr Scientist, Process Development

职位描述

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description

This role is responsible for the development and optimization of chemical processes for the manufacture of drug substances supporting clinical and commercial programs. The scientist will plan, execute, and interpret laboratory experimentation to advance process understanding, product quality, and manufacturability, including route selection, step optimization, and scale‑up. Working collaboratively with senior scientists and cross‑functional partners, the role contributes to overall project strategy and provides technical leadership to project teams.

The position includes day‑to‑day oversight of research activities and project team members, preparation and review of technical documentation such as development reports and Master Batch Records, and hands‑on support of laboratory and large‑scale manufacturing activities conducted under cGMP. The successful candidate will act as a subject matter expert across functions, ensure compliance with safety, quality, and environmental standards, and demonstrate strong scientific judgment, communication, and leadership capabilities while operating in a collaborative, multidisciplinary environment.​

Key Responsibilities:

• Be responsible for developing chemical processes for the manufacturing of drug substances

• Demonstrates technical knowledge, scientific creativity, and collaboration skills in the development and execution of research for the preparation of novel chemical substances

• Plans, executes and analyzes laboratory experimentation to advance the knowledge of production and quality attributes of drug substances

• Proposes alternative chemistry, including new route selection and step optimization

• Provides regular updates to supervision and proposes future research directions

• In collaboration with senior scientists, develops project strategy for manufacturing of drug substances to support clinical studies and commercialization

• Responsible for the day to day management of project team members and research assignments, including designing and interpreting of experimentation

• Prepares and reviews technical documents including research reports, process development reports, and documentation for the manufacturing of chemical substances e.g. Master Batch Records (MBRs)

• Collaborates across functional areas including analytical chemistry, quality assurance, and manufacturing to accomplish project goals. Acts as a subject matter expert for cross-functional teams and research personnel

• Provides technical support for manufacturing processes performed under cGMP in laboratory manufacturing and large-scale manufacturing operations

• Ensures that all experimentation is carried out in accordance with appropriate standard operating procedures (SOPs), maintaining quality, safety, and environmental standards
  

Basic Qualifications:

• 8+ Years with BS
  OR
• 6+ Years with MS
  OR
• 0+ Years with PhD/PharmD

Preferred Qualifications:

• PhD in Organic Chemistry (or related discipline) and 2+ years of relevant experience minimum. We prefer a PhD with 2-10 years ideally, level will be commensurate with experience OR

• MSc degree with extensive industry experience (6+ years) OR

• BSc degree with extensive industry experience (8+ years)

• Experience in planning and executing multi-step synthesis of organic molecules

• Experience scaling up synthetic routes and developing safe processes

• Familiarity with purification and analytical techniques, including HPLC, LCMS and NMR

• Familiarity with pilot plant and/or plant operations, and experience with generating master batch records is an asset

• Familiarity with process validation, regulatory filings and cGMP regulatory guidelines is an asset

• Strong desire to work in multi-disciplinary teams, learn new skills and solve problems

• Excellent verbal and written communication skills, and strong interpersonal collaboration skills

• Must think critically and creatively and be able to work independently to determine appropriate resources for resolution of problems

• Strong organizational and planning skills

• Experience with project and people management is an asset
  

People Leader Accountabilities:

• Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams.

• Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and realize their purpose.

• Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.

The salary range for this position is: $169,320.00 - $219,120.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

For jobs in the United States:

Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

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Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

Please apply via the Internal Career Opportunities portal in Workday.