Scientist, Analytical Ops

Job Description (Translated)

Scientist, Analytical Ops Job Description Gilead is seeking a Ph.D. scientist with strong background on Immunology and Virology with extensive experience developing primary cell-based assays/methodologies in the Biologics Development and Manufacturing facility in Oceanside, CA. The successful candidate will join Potency and Functional Characterization team to develop therapeutic biologics of cancer, inflammation, and infectious diseases. Specific Responsibilities: Collaborate with the Gilead research, non-clinical, clinical project teams to understand the mechanism of actions of biologics pipeline molecules, and works with drug substance and drug product, structural characterization teams to support late-stage process development and optimization for complex biologics. The successful candidate will identify and deploy orthogonal functional characterization methods including cell-based and ligand-receptor binding assays, lead or participate in function-structure relationship studies, and critical quality attribute assessment. Lead cell line engineering efforts including target overexpression and reporter gene systems to support cell-based assay development. Hands-on experience with multi-color flow cytometry and primary immune cell-based assays (e.g., ex vivo T cell-mediated target cell killing, NK-mediated antibody dependent cellular cytotoxicity) assays is required. The successful candidate will be expected to demonstrate hands-on technical leadership in the laboratory, oversee and delegate experimental/project responsibilities as needed, independently champion technology development projects, be involved in new assay evaluation and optimization. The applicant should be an effective communicator of ideas, project goals and results to team members across cross-functional roles/departments. Candidates should be self-motivated and organized, familiar with the relevant literature, and enjoy scientific investigation and thinking, proactively identify issues and develop solutions in a collaborative multidisciplinary environment. Basic Qualifications: 6+ Years with BS 4+ Years with MS 0 to 5 Years with PhD Preferred Qualifications: Ph.D. degree in Immunology, Cell and Molecular Biology or a related scientific discipline with 0 to 5 years including post doc experience that demonstrates an expertise in flow cytometry and cell-based assay development. Good communication skills (both verbal and technical) and interpersonal skills are required. Maintains in-depth knowledge of state-of-the art principles and theories, applying such knowledge to the research direction that supports Company interests. Demonstrates technical proficiency, scientific creativity, collaboration with others and independent thought in suggesting experimental design and research strategy. Must think critically and creatively and be able to work independently, determine appropriate resources for resolution of problems and have strong organizational and planning skills.