Scientist, Biology

Descripción del trabajo

Scientist, Inflammation Biology

The Inflammation Biology group at Gilead Sciences (Foster City, CA) is seeking a talented and highly motivated Scientist to join our research group. The successful candidate will contribute to the discovery, research, and development of novel therapeutics to address unmet clinical needs in metabolic, inflammatory, and fibrotic diseases including Metabolic Dysfunction-Associated Steatohepatitis (MASH), Primary Biliary Cholestasis (PBC) and Idiopathic Pulmonary Fibrosis (IPF). As a member of a cross-functional team, the candidate will support and lead projects across discovery research and into early clinical development. The successful candidate will have opportunities for career growth through acquisition of new skills, experiences, and professional relationships in a fast-paced and resource-rich Research environment.

Key Responsibilities:

• Responsible for designing and executing scientific research for the discovery of drug targets and the development of drug candidates.
• Independently design, conduct, and analyze in vitro and in vivo experiments to support target discovery and validation.
• Evaluate new technologies and generate scientific hypotheses to enhance understanding of disease mechanisms.
• Manage multiple projects simultaneously and work cross-functionally with colleagues in Bioinformatics, Protein Engineering, and Medicinal Chemistry.
• Present research findings and recommendations to senior staff, prepare research reports and peer-reviewed manuscripts; contribute to INDs and patent filings.
• Think critically and creatively, stay informed of the latest developments in the field and proactively ideate to accelerate early-stage discovery programs.

Basic Qualifications:

• PhD in molecular or cell biology, or related field; PhD and 2+ years of post-doctoral training is preferred.
• Experience in target identification strategies through use of genomics, human tissue-based analysis and transcriptomics/proteomics, and/or phenotypic screens.
• Hands-on experience with pre-clinical in vivo models of disease is preferred.

Preferred Knowledge, Experience and Skills:

• Subject matter expertise in fibrosis, metabolic disease and/or inflammation with a strong track record of scientific accomplishments, demonstrated by peer-reviewed scientific publications in well-recognized journals.
• Demonstrated ability to define and implement critical-path studies to support hypothesis-based research.
• Excellent written, verbal, and interpersonal communication skills.