Principal Scientist, Oncology Research

职位描述

At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers.

We set and achieve bold ambitions in our fight against the world’s most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come. As a Principal Scientist of Tumor-Intrinsic Biology you will lead a discovery lab and collaborate across functions to pursue creative science, develop strategic initiatives, and evaluate external partnerships, in the service of discovering novel medicines that impact patients’ lives.

Additional Key Responsibilities

Leadership

• Mentor a lab-based scientific team, advancing their projects and careers.

• Serve as a scientific and technical thought leader throughout the Research organization.

• Collaborate across functions to guide interdisciplinary projects, with experts in oncology, immune-oncology, protein engineering, chemistry, translational medicine, biomarkers and clinical development. Identify project risks and mitigate effectively, while communicating with project teams and other leaders.

Innovation and Scientific Acumen

· Proactively ideate to accelerate early-stage discovery activities, enhance understanding of disease mechanisms, and develop new technologies and novel targeting modalities.

• Develop expertise in relevant scientific fields and the external landscape, including the scientific literature, conference proceedings, and competitive programs. As an in-house expert, propose creative and rigorous research to discover, validate and understand targets.

• Think critically and creatively, emphasizing nimble decision making that balances risk-taking with thoughtful experimentation within the strategic/competitive context to fuel a differentiated pre-clinical pipeline.

• Contribute expertise to multi-disciplinary due diligence teams to evaluate and recommend partnerships and acquisitions.

• Contribute to research reports, INDs, and patent filings.

• Establish an external presence through peer-reviewed publications, conference presentations, and external collaborations.

Knowledge, Experience and Skills

• Ph.D. degree and 5+ years of experience (tumor biology, drug discovery, target identification and technology development), with post-doctoral training highly preferred.

• Strong track record of impact in scientific field, including first- or senior-author publications in peer-reviewed journals and conference presentations.

• Strong knowledge base in cancer genomics and oncogenic signaling.

• Broad technical skillset of cutting-edge methods and models of cancer, in vitro and in vivo, with experience in biochemically analyzing protein (and protein-nucleic acid) complexes a plus.

• Demonstrated success in leading research teams to productive, creative, data-driven decisions.

• Team-centric mindset, with proven managerial excellence and ability to motivate skilled team members from diverse backgrounds.

• Excellent communication and interpersonal skills.