Principal Scientist, Oncology

Job Description

Gilead's mission is to discover, develop, and deliver therapies that will improve the lives of patients with life-threatening illnesses worldwide.

Position Overview:

We are seeking a highly motivated and creative Principal Scientist to support Gilead’s growing ADC portfolio. The successful candidate will be an integral senior member of a high performing research team dedicated to identifying and validating novel ADC modalities for therapeutic applications through internal and external efforts. In this role, the candidate will manage an internal research team and interact in a highly cross-functional manner across multiple departments to ideate and advance projects. In addition, the candidate will use its extensive knowledge of the ADC field to support external diligence efforts and evaluate assets as well as novel platforms.

Specific Responsibilities:

• Design and lead cross-functional ADC projects leveraging internal and external resources

• Role is expected to lead from the bench and actively participate in the design and execution of critical experiments

• Significantly contribute to the evaluation of external asset and platform opportunities

• Support the development of a comprehensive ADC strategy at Gilead through project ideation and scientific experimentation

• Manage reports and lead a productive research team dedicated to identifying and validating new tumor-associated antigens for given cancer indications, new ADC payloads, and optimal binders for future internal and external ADC projects.

• Identify, establish, and manage strategic external collaborations with academic institutions and biotech companies to support ADC programs

• Contribute to the preparation of scientific reports, manuscripts, and patent applications.

Minimum Qualifications:

• Ph.D. in Cell Biology or related field.

• 5+ years of relevant experience with PhD; 6+ Years relevant industry experience and with postdoctoral training preferred

• Minimum 3 years in a managerial role with demonstrated team management experience.

• Proven track record of publications and/or patents

• Deep expertise and understanding of ADCs and the competitive landscape as well as prior participation in external diligences within the ADC field

• Demonstrated ability to design and execute in vitro and in vivo studies for ADC evaluation and optimization.

• Familiarity with additional novel ADC formats and payloads is a plus

• Proficiency in data analysis tools and statistical software; experience with AI/ML applications is a plus

• Exceptional problem-solving abilities and scientific judgment

• Strong project management skills with ability to oversee multiple projects simultaneously while maintaining high quality standards.

• Excellent verbal and written communication skills with the ability to influence and collaborate effectively across disciplines and present to executive leadership.

Basic Qualifications:

5 years industry experience with PhD OR 8 years of industry experience with Masters degree OR 10 years of industry experience with Bachelors degree

People Leader Accountabilities:

•Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams.

•Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and realize their purpose.

•Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.