
Research Scientist
United States - California - Foster CityResearchRegularDescription de l'emploi
Gilead Sciences headquartered in Foster City, CA is seeking a talented and motivated Research Scientist to join our Oncology Research group. Our collaborative and interdisciplinary research team utilizes state-of-the-art technologies and innovative methodologies to advance medicines into the clinic. The successful candidate will lead and contribute to the discovery, research, and development of novel therapeutic agents to address unmet medical needs of cancer patients. The candidate will be encouraged to take advantage of career growth opportunities, including developing new technical skills, research experiences, and professional relationships in a fast-paced and resource-rich environment.
Key Responsibilities
Lead the initiation and/or advancement of oncology projects into the pipeline using in vitro and in vivo methodologies
Participate in nomination of new targets
Direct, independently plan, execute, analyze, and interpret complex experiments to identify or validate novel targets, elucidate target biology, elucidate drug candidates’ mechanism of action
Develop assays to measure pharmacodynamic markers, kinetics of drug response
Train and mentor junior scientists or direct members of project teams in the initiation and execution of experimental plans
Manage multiple projects simultaneously and work cross-functionally with colleagues in the oncology, in vivo pharmacology, bioinformatics, medicinal chemistry, DMPK and other relevant functions
Proactively evaluate new technologies and implement new approaches to enhance our understanding of disease mechanisms
Presents research findings and recommendations to leadership, author and contribute to research reports, manuscripts, IND and patent filings
Think critically and creatively, work independently as well as a part of collaborative teams
Have strong organizational and planning skills
Cultivate a culture that embraces scientific excellence, urgency, partnerships with key stakeholders, continuous learning and improvement, taking proactive role in personal growth and development
Basic Qualifications
PhD degree in related life sciences
Master's degree in related life sciences and 4+ years of experience in cell biology, molecular biology, or biochemistry in biotechnology or pharmaceutical industry OR
Bachelor's degree in related life sciences and 6+ years of experience in cell biology, molecular biology, or biochemistry in biotechnology or pharmaceutical industry
Preferred Qualifications:
PhD degree in Cell Biology, Molecular Biology, or Immunology with 3+ years postdoctoral training in cancer cell biology supported by impactful publications
Deep and broad knowledge of cancer biology, oncology targets and signaling pathways, demonstrated scientific rigor, independence and scientific achievements
Demonstrated experience in elucidating biology of targets in oncology utilizing genetic and pharmacological tools
Passionate about hands-on experimental work, able to critically evaluate experimental results and make data-driven decisions
Excellent technical skills, extensive experience in broad range of molecular and cell biology techniques and superb knowledge of various experimental methodologies including but not limited to gene expression platforms, knockdown, knockout, knock-in and over-expression of genes, flow cytometry, MSD ELISA, high-content imaging
Technical skills applicable to chromatin biology is a plus
Demonstrated working experience with in vivo tumor models is a plus
Attention to quality and details, with excellent record keeping skills
Excellent communication and interpersonal skills