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Associate Scientist, Analytical Operations

United States - California - Santa MonicaProcess/Product Development & OperationsRegular

Job Description

Associate Scientist

Product Attribute Sciences, Analytical Ops, Process Development

Job Overview

Product Attribute Sciences is seeking a talented and highly motivated Associate Scientist with a background in immunology, cell biology, and/or cancer biology. The ideal candidate will have expertise with high-throughput molecular techniques to assess immune cell function using various platforms and technologies, e.g. genomics, transcriptomics and proteomics. In addition, the successful candidate will have experience in cell-surface profiling to assess the functional phenotype of immune cells. The SAS will perform innovative characterization studies to interrogate quality attributes of Kite’s cell therapy products. The SAS will collaborate cross-functionally with Process Design, Research, Translational Medicine, and/or Quality teams in an effort to enable in-process attribute and product understanding. The ideal candidate should be adaptable and willing to accept new roles and responsibilities that could evolve over time.

Responsibilities include but are not limited to:

  • Design and execution of novel and innovative characterization studies using both cell-based assays and high-throughput molecular and cellular techniques to interrogate immune cell biology and function
  • Handling and maintenance of associated materials, such as cells and reagents, in an established and controlled manner
  • Generation, analysis, interpretation, documentation and presentation of experimental data
  • Author, review, and edit technical documents, i.e. SOPs and/or reports

Requirements:

  • M.S. in Biology, Immunology or related discipline with 3+ years of industry experience, or
  • B.S. in Biology, Immunology or related discipline with 5+ years of industry experience

Additional Qualifications:

  • Experience with high throughput single-cell molecular techniques including, but not limited to, 10X Genomics , Tapestri, BD Rhapsody, and/or Nanostring platforms
  • Experience and technical understanding of ELISA, MSD, Luminex-based assays, Incucyte, and/or ddPCR
  • Experience in cell-surface profiling using CyTOF mass cytometry, 40+ color flow cytometry, cell sorting, and/or ImageStream cell imaging is a plus
  • Experience with cell culture (aseptic techniques, human cell line expansion); experience with human primary cell culture and isolation of immune cells from multiple tissues is preferred.
  • Proficient in the use of Microsoft Office, data analysis software (Prism, JMP) and other applications
  • Strong scientific writing and presentation skills
  • Ability to think critically and demonstrate troubleshooting and problem-solving skills
  • Highly collaborative with excellent interpersonal, verbal and written communication skills
  • Self-motivated, detail-oriented, and willing to accept temporary responsibilities outside of initial job description
  • Comfortable in a fast-paced environment

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