Associate Scientist, Analytical Operations

Job Description

At Gilead we believe every employee deserves a great leader. As a people leader now or in the future, we expect that you will model and create an environment of inclusion, be intentionally focused on the hiring, development, growth and retention of talent, and empower teams to align and achieve goals.

Job Description

Department: Analytical Development

Location: Santa Monica, CA

Position: Associate Scientist 

Analytical Development, Process Development

Analytical Development is looking for a talented and highly motivated Associate Scientist (AS) with a background in molecular biology, specifically ddPCR or qPCR-based assays, to join a team focusing on the characterization and/or release assay development for drug substance (LVV/RVV) and drug product for T cell therapies. The incumbent will be responsible for executing ddPCR based analytical method development with minimal supervision, generate, analyze, interpret, and present experimental data, and carefully document resultant information in ELNs.  Should be able to write SOP, protocols, and reports. This is a Lab based role which requires to be onsite. 

Responsibilities and Duties

•    With minimal supervision, execute and document ddPCR/qPCR method development (GC, VCN, IFU and impurities) activities in support of process development, product release and stability, and product characterization of drug substance (vector) and T cell drug products.

•    Perform qualification studies for Analytical methods per established guidance and ICH guidelines. 

•    Maintain accurate documentation of experiments in ELN and reports.

•    Data analysis (JMP), interpret the results and presentation at the group and cross functional meetings. 

•    Work closely with QC during knowledge, method transfer and co-qualification.

•    Contribute to technical documents (e.g., development reports, SOPs, and technical reports).

•    Maintain, calibrate and operate analytical equipment and instruments.

•    Ensure that departmental areas are maintained per 5S guidelines.

Basic Requirements

•    MA/MS/MBA with 3+ years of relevant experience; OR

•    BA/BS with 5+ years of relevant experience

Preferred Qualifications

•    Background in immunology, molecular biology, cell biology. 

•    Relevant ddPCR/qPCR assay development or assay execution experience is a must. Experience with molecular biology techniques (transduction, titer, DNA/RNA extractions, cDNA synthesis, Primer designs, PCR/ddPCR) is a must.

•    Knowledge of T cell biology and immune cell therapy (e.g., viral vectors, CAR T functional assays) is strongly desired.

•    Experience with Mammalian cell culture. 

•    Prior industrial experience is a plus. 

•    Proven ability to work in a fast-paced environment, meet deadlines,   prioritize work on multiple projects.

•    Excellent skills in Microsoft Office, data analysis software (e.g. JMP, Graphpad Prism, Geneious, Snapgene, SoftMax Pro), and other applications. 

•    Ability to think critically and demonstrate troubleshooting and problem-solving skills.

•    Overall understanding of drug development process and its impact on projects, goal and timelines is preferred.

•    Ability to work independently and as part of a team

•    Occasional Travel 

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The salary range for this position is: $101,830.00 - $131,780.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

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