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Associate Scientist – Translational Medicine

United States - California - Santa MonicaResearchRegular

Job Description

The Associate Scientist will support the Clinical Pharmacology team and biomarker operational activities.  As a member of the Translational Medicine team, you will be at the intersection of Research and Clinical Development, providing valuable insight into the function of CAR T cells in patients.  You will support characterization of cell therapy product and clinical samples. The role will further involve close collaboration with Research and Translational Medicine Departments as well as Sample Management team on assay development, optimization, patient sample tracking and analysis.  You will report to a Senior Research Scientist, Biomarker Lead.


  • Assist in planning and executing T cell-based assays, and single-cell flow cytometric analysis 
  • Perform diverse data analysis/review, documentation and reporting of results via data transfer to clinical databases
  • Assist in clinical trial pharmacology data verification
  • Track clinical sample inventory and create shipping requests using sample management systems
  • Laboratory management - organize and manage inventory of laboratory reagents; implement reagent optimization, lot-checking and restocking; equipment maintenance
  • Coordinate requests and queries with CROs/vendors
  • Support assay development, validation, and internal and external transfer of assay methods
  • Write, review and edit procedural documents including SOPs, development protocols and reports
  • Contribute to internal and cross-functional scientific discussions
  • Assist in the preparation of data packages for publication, presentation and/or submission to regulatory agencies
  • Provide user training on instruments, sample analysis, and cross-train analysts on analytical methods
  • Contribute to selection and implementation of new assay technology capabilities
  • Participate in clinical trial planning meetings for Clinical Pharmacology support
  • Additional responsibilities may be assigned to reflect changes in business processes

Basic Qualifications

Master’s Degree and 3+ years of scientific experience


Bachelor’s Degree and 5+ years of scientific experience


High School Degree and 9+ years of scientific experience

Preferred Qualifications

  • Degree in immunology, molecular biology, cell biology or a closely related field
  • Experience with laboratory techniques and experimental design with an emphasis on cell-based assays, such as immunoassays (e.g. ELISA, Luminex, MSD), flow cytometry, cell culture techniques, nucleic acids and protein extraction, single cell genomics
  • Familiarity with GCLP compliance standards
  • Experience communicating with vendors/CROs
  • Strong organization and record-keeping skills
  • Strong collaboration, excellent interpersonal and communication skills
  • Familiarity in the areas of tumor biology, immunology and immuno-oncology
  • Comfortable in a dynamic environment and able to adjust workload based upon changing priorities
  • Microsoft office skills (Word, Excel, PowerPoint)