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Process Engineer

United States - California - Santa MonicaProcess/Product Development & OperationsRegular

Job Description

Everyone at Kite is grounded by one common goal – curing cancer. Every single day, we seek to establish a direct line between that purpose and our day-to-day work. Would you like to join us in this mission?

Kite is seeking a highly motivated individual to join our Allogeneic Process Development group as a Process Engineer. The Process Engineer will work independently as well as collaboratively within a high-functioning project team. Bringing technical knowledge, initiative, strong scientific integrity, and an enthusiasm for learning, the incumbent will make significant contributions within the group. The incumbent will contribute highly in the evaluation and implementation of key technologies and improvements to the allogenic cell therapy processes including but not limited to vector and media development, cell engineering, improved screening & selection technologies and support drafting of protocols & technical reports to support Kite’s engineered Allogeneic cell therapy products. 

Responsibilities of the Process Engineer – Allogenic Process Dev. include:

  • Develop and execute protocols related to media and buffer preparation, cell culture, cell engineering, cell sorting, cell cryopreservation and other activities as needed
  • Evaluate impact of process parameters on product performance and develop processes to support early and late stage process dev. studies 
  • Collaborate and execute studies to develop a thorough understanding of operating parameters of unit operations for process improvements
  • Participates in decision-making processes within the project team by actively engaging in scientific and technical discussions
  • Enters and analyzes data to support project leads in preparation of presentation, data graphs and technical reports
  • Manages samples and inventory related to each experiment
  • Write and review technical and summary reports
  • Interface cross-functionally with Research, Process Design, MSAT, Manufacturing, Supplier Quality, Supply Chain, Quality, Regulatory, and external partners as needed

Requirements:

  • BS/BA Degree in Biochemical Engineering, Chemical Engineering, Biotechnology or related fields with 2+ years of cell culture and/or cell therapy manufacturing and process development experience 
  • MS/MA Degree in Biochemical Engineering, Chemical Engineering, Biotechnology or related fields with 1+ years of the aforementioned experience
  • High School Diploma with 5+ years of the above-mentioned experience

Preferred Qualifications:

  • Aseptic Cell culture experience at different scales using adherent and/ or suspension platforms from static culture flasks to suspension bioreactors
  • Experience with cell engineering and related technologies including electroporation, transduction and cell sorting technologies e.g. FACS
  • Molecular biology experience with focus on vector development and molecular analytical tools including gel electrophoresis, RT-PCR, dd-PCR and other related technologies 
  • Practical demonstration of hands on process development including use of statistical design of experiment
  • Ability to work and collaborate in cross functional teams, research, development, manufacturing in a fast pace, dynamic team setting
  • Ability to think critically, analytically and have demonstrated troubleshooting and problem-solving skills based on deductive reasoning
  • Excellent interpersonal, verbal and written communication skills
  • Fluent with Microsoft office applications, statistical analysis tools (JMP/ Minitab) and data management tools
  • The ability to accommodate occasional weekend and evening work and critical business-related travel, if required