Senior Research Associate I – Biologics Discovery

职位描述

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description

About Gilead Sciences:

Gilead is a research-based biopharmaceutical company that discovers, develops, and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world.

Role Overview

The Antibody Discovery group is a specialized team within the Protein Therapeutics function that is responsible for the discovery of biologics for drug candidates and critical reagents. We are currently seeking a highly motivated Senior Research Associate I to join the team in this newly created position. The successful candidate will contribute to antibody discovery efforts as part of a cross-functional team focused on identifying novel biologic modalities to support all therapeutic areas at Gilead.

Job Responsibilities:

In this fully on-site, laboratory-based role, the successful candidate will support efforts to generate novel antibody-based therapeutics and reagents. The ideal candidate will be self-motivated, have a strong expertise in rodent in vivo work, with general knowledge of hybridoma and single B-cell antibody discovery workflows.

• Conduct rodent immunizations via tail vein, IV, IP, IM or SubQ injection.
• Proficient with tissue collection and processing, e.g. blood, spleen, lymph nodes, or other tissues of interest for downstream analysis.
• Maintain and ensure a safe laboratory environment and work practices. Follow standard operating procedures (SOP) and IACUC protocols.
• Opportunities to lead antibody discovery projects and represent the group on project teams.
• Collaborate with cross-functional teams to support functional characterization of antibodies.
• Contribute to the development and optimization of innovative antibody discovery platforms.
• Present scientific results in multiple settings and attend project team meetings.
• Maintain accurate experimental records and documentation in compliance with regulatory standards and company policies.

Qualifications:

• M.S./B.S. degree with at least 3-5 years of laboratory experience utilizing techniques or methods required by the position.
• Must be able to work with mouse colonies.

• Experience with general laboratory techniques, especially basic vivarium techniques (mouse handling, injection, tissue harvesting) is required.
• Experience with immunization of varieties of immunogens including DNA, mRNA is a plus.
• Experience with in vivo imaging is a plus.
• Experience in ELISA, FACS, and mammalian cell culture skills is a plus.
• Willingness and ability to learn new methods and skills.
• Ability to work independently and as a member of a research team.
• Highly organized and capable to track multiple, complex workflows.
• Strong written and oral communication skills, with an ability to work in a dynamic, collaborative, and evolving environment.

The salary range for this position is: $92,820.00 - $120,120.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance.

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